By Richard Gale and Gary Null

Cautionary Tale: This COVID Vaccine Could Heighten HIV Risk for Some, Scientists Warn

In a letter published in The Lancet, several researchers raised questions about the potential for adenovirus-based vaccines to increase the risk of HIV for some recipients.

In a letter published in The Lancet, researchers warn that the adenovirus vector technology being used around the world to develop vaccines against SARS-Cov-2 could put populations at risk of developing HIV infections.

The researchers — from the Fred Hutchinson Cancer Research Center in Seattle, the University of California at San Francisco and the National Institute of Allergy and Infectious Diseases — said the use of adenovirus 5 vector (Ad5) vaccines could have a devastating impact on regions in the developing world that are still plagued by high HIV rates. People with pre-existing immunity to adenovirus are most susceptible for contracting HIV, the researchers said.